A clinical obserbation in terms of etiologic factors was made on the consecutive 100 cases of hydatidiform mole for the past 7 years.
1) The presence of anemia could be recognized in all of the cases, which belonged in general to the lower class of living standard and the malnutrition related closely with the anemia seemed to result in higher incidence of hydatidiform mole.
2) Higher was the incidence of this affection in thson in those who were from rural area than from city, which seasonal predilection lying in May to July.
3) The rate of premature delivery and spontaneous abortion including the hydatidiform mole ranged 24.2% of total pregnancies. The hydropic change of chorionic tissues, which was encountered frequently in abortion, should therefore be guarded as the precursor of hydatidiform mole.
4) Chronic -debilitating and metabolic disease were noted in 28 cases, 18 of which were tuberculosis. This disability should also be regarded as a causative- factor, accelerating malnutrition:,
5). The duration of West feeding period in 80 cases was as follows; within one year -in 1, between one and two years in 22, and over 2 years. in 57. Of the 80, the 23 ceased,, feeding before. the occurrence of the affection, which the rest was still in lactation at the time of the outset.
This data strongly suggest that the possible protracted endocrine imbalance, the severity of malnutrition and the retardation of its amelioration might have resulted from the prolonged lactation, plying as another etiologic factor of Hydatidiform Mole.
6) Overall incidence was highest in, third decade, though from fourth decade the rate of
occurrence showed pronounced increase in proportion to the number of pregnancy.
7) Relevant to co-existence of the increase of age and parity was the higher incidence´ of Hydatidiform Mole.
8) The period of latest feeding in relation to the number of parity could be divided into 3 groups; one and a half years under 2, two and a half years between 3 and 5, three ´and a half years over 6. A definite trend of prolonged lactation could be traced as the number of parity increased..
9) Regarding the: higher incidence of hydatidiform mole, there seems to exist an-intimate relationship to the coexistence of three factors; the increase of parity, prolonged lactation and the older age of the patient.
10) The percentage of hydatidiform mole related to the total. number of pregancy occupied one percent.
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